Treatment of SAPHO with pamidronate
نویسندگان
چکیده
منابع مشابه
SAPHO syndrome treated with pamidronate.
A middle aged man presented with a 4 year history of painful swelling of both knees and pustular acne on his back. The MRI scan of the knees showed gross synovitis, so did the histopathology of the synovium. A diagnosis of SAPHO syndrome was made and he was treated with IV pamidronate. His pain reduced and acne completely cleared up on therapy. A dermatologist has rarely made a diagnosis of SAP...
متن کاملSAPHO syndrome treated with pamidronate: an open-label study of 10 patients.
BACKGROUND In recent years the SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) has been encountered more frequently. However, clinical evidence indicating superiority of a specific therapeutic modality is still absent. Pamidronate, a second-generation bisphosphonate, has a pronounced effect on bone metabolism by suppressing bone resorption. We report our clinical experie...
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© 2010 The Authors. doi: 10.2340/00015555-0822 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 SAPHO syndrome is a rare condition of unknown pathogenesis originally described by Chamot et al. (1) in 1987. Onset usually occurs in young adults, with no differences between sexes and it is manifested by synovitis, acne, pustulosis, hyperostosis and osteitis. Of paramount impor...
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چکیده ندارد.
15 صفحه اولSustained remission of SAPHO syndrome with pamidronate: a follow-up of fourteen cases and a review of the literature.
OBJECTIVE To evaluate the efficacy of intravenous (i.v.) pamidronate in patients with SAPHO syndrome refractory to first line treatments and to review the available literature on pamidronate for this indication. METHODS We report 14 cases of SAPHO syndrome refractory to non-steroideal anti-inflammatory drugs (NSAIDs), glucocorticoids and disease modifying anti-rheumatic drugs (DMARDs) treated...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2002
ISSN: 1460-2172
DOI: 10.1093/rheumatology/41.10.1196